Definition and Intelligent Extraction of Texture Features of Vestibular Schwannoma Based on MRI Imaging

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dc.contributor.authorSineglazov Victor
dc.contributor.authorShevchenko Maksym
dc.date.accessioned2026-05-25T12:20:02Z
dc.date.available2026-05-25T12:20:02Z
dc.date.issued2025
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dc.description.abstractThe scientific work is devoted to the development of a method for intelligent extraction of textural features of vestibular schwannomas based on magnetic resonance imaging images for predicting tumor growth. The VS-MC-RC2 dataset was analyzed (421 timepoints, 189 patients, 1990–1999). The ML dataset consists of 211 samples (74 growing, 137 stable, imbalance 1.85:1). Gray Level Co-occurrence Matrix and Gray Level Size Zone Matrix matrices, shape features, wavelet transform, and the PyRadiomics v3.0.1 library were used to extract features from T1C images (priority) and T1 images (fallback) with the following parameters: bins = 32, δ = 1 voxel, 13 3D directions. Model v2 (107 original features) achieved an AUC of 0.618. Model v3 (851 features + 8 wavelet decompositions) achieved an AUC of 0.712 (+15.2%). Validation was performed using 10-fold cross-validation with an 80/20 train/test split. Among the top 15 features, 73% were wavelet features (LHH, LLH, HLH). The best feature, original_glszm_ZoneEntropy (F = 12.67, threshold = 4.51), correlates with the Antoni A/B tissue ratio and the proliferative activity of the tumor. Роботу присвячено розробці метода інтелектуального вилучення текстурних ознак вестибулярних шванном на основі МРТ-зображень для прогнозування росту пухлини. Проаналізовано датасет VS-MC-RC2 (421 timepoint, 189 пацієнтів, 1990-1999). ML датасет: 211 зразків (74 зростаючі, 137 стабільні, дисбаланс 1.85:1). Використано матрицю співзустрічальності рівнів сірого, матрицю зон рівнів сірого, Shape Features, Wavelet Transform, бібліотеку PyRadiomics v3.0.1 для вилучення ознак з T1C-зображень (пріоритет) та T1 (резерв) з параметрами: bins = 32, δ = 1 voxel, 13 3D напрямків. Model v2 (107 оригінальних ознак): AUC 0.618. Model v3 (851 ознак + 8 вейвлет-декомпозицій): AUC 0.712 (+15.2%). Валідація: 10-fold CV, навчальна/тестова 80/20. Топ-15 ознак: 73% wavelet features (LHH, LLH, HLH). Найкраща: original_glszm_ZoneEntropy (F = 12.67, threshold = 4.51), що корелює з співвідношенням Antoni A/B тканин і проліферативною активністю пухлини.
dc.identifier.citationSineglazov V. M. Definition and Intelligent Extraction of Texture Features of Vestibular Schwannoma Based on MRI Imaging / V. M. Sineglazov, M. V. Shevchenko // Electronics and Control Systems, No 4(86) – Kyiv: TOV “Al'yant”, 2025. – pp. 72–79
dc.identifier.issn1990-5548
dc.identifier.issnDOI:10.18372/1990-5548.86.20626
dc.identifier.urihttps://er.kai.edu.ua/handle/KAI/70069
dc.language.isoen
dc.publisherState University "Kyiv Aviation Institute"
dc.relation.ispartofseries4; 86
dc.subjectvestibular schwannoma
dc.subjectmagnetic resonance imaging
dc.subjectradiomics
dc.subjectgray level co-occurrence matrix
dc.subjectgray level size zone matrix
dc.subjectwavelet
dc.subjectRandom Forest
dc.subjectPyRadiomics
dc.subjectвестибулярна шваннома
dc.subjectмагнітно-резонансна томографія
dc.subjectradiomics
dc.subjectматриця співзустрічальності рівнів сірого
dc.subjectматриця зон рівнів сірого
dc.subjectвейвлет
dc.subjectRandom Forest
dc.subjectPyRadiomics
dc.subject.udc004.855.5(045)
dc.titleDefinition and Intelligent Extraction of Texture Features of Vestibular Schwannoma Based on MRI Imaging
dc.title.alternativeВизначення та інтелектуальне вилучення текстурних ознак вестибулярної шванноми на основі використання МРТ зображень
dc.typeArticle

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